Wound healing angiogenesis: A perspective of nurse

Wounds healing can be a clinical challenge, and a cause of morbidity and mortality. One aspect of wound repair that plays an important role for adequate healing is the creation of new blood vessels from pre-existing vessels; this process is called angiogenesis. Clinically, new capillaries first become visible in the wound bed 3 – 5 days after injury, and their appearance is synonymous with granulation tissue, which acts as a matrix for proliferating blood vessels, migrating fibroblasts and new collagen. Impaired granulation is a hallmark of chronic wounds, as encountered in patients with type 2diabetes and venous or arterial insufficiency [1]. A number of researchers have reported, chronic nonhealing wounds are impacted by insufficient angiogenesis; decreased vascularity and capillary density delay wound closure. This perspective describes the principles of wound healing angiogenesis, especially to the wound nurse specialist, in order to identify the impact and interventions that may promote wound repair. Through this perspective, nurse specialists are expected to understand the concept of angiogenesis comprehensively. Clinical nurses with good insight of angiogenesis must be able to select the appropriate dress which suitable for wound healing. Utilizing modern bandage in acute and chronic wound management will accelerate the formation of growth factors that induce angiogenesis, and production of blood vessels.