Open AccessOn the use of utility functions for optimizing phase II/phase III seamless trial designs
Author(s) -
Jihane Aouni,
JeanNoël Bacro,
Gwladys Toulemonde,
P. Colin,
Loic Darchy,
Bernard Sébastien
Publication year - 2021
Publication title -
hal (le centre pour la communication scientifique directe)
Language(s) - English
DOI - 10.35248/2167-0870.20.10.415
Subject(s) - sample size determination , phase (matter) , computer science , interim , variance (accounting) , sample (material) , optimal design , fisher information , mathematical optimization , statistics , mathematics , machine learning , chemistry , accounting , organic chemistry , archaeology , chromatography , business , history