Open AccessRelationship of Kidney Tubule Biomarkers with Cognition among Community-Living Elders in the Health ABC Study
Author(s) -
Lindsay M. Miller,
Mark J. Sarnak,
Dena E. Rifkin,
Onur Potok,
Linda F. Fried,
Stephen B. Kritchevsky,
David A. Drew,
Michael G. Shlipak,
Joachim H. Ix
Publication year - 2022
Publication title -
kidney360
Language(s) - English
Resource type - Journals
ISSN - 2641-7650
DOI - 10.34067/kid.0004022022
Subject(s) - cognition , baseline (sea) , lipocalin , urine , urinary system , cognitive decline , longitudinal study , medicine , gerontology , effects of sleep deprivation on cognitive performance , psychology , dementia , psychiatry , biology , pathology , fishery , disease
Higher baseline urinary neutrophil gelatinase-associated lipocalin was associated with worse cognitive scores at baseline.Lower concentrations of baseline serum bicarbonate (higher is better) were associated with lower cognitive scores at baseline.We found no associations with urine markers with longitudinal changes in cognition.