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Synthesis, Characterize and Evaluation of anti-bacterial and anti-fungal activity of thiazines
Author(s) -
Arsalan Sarmad,
Razia Sultana,
B. Salman
Publication year - 2019
Publication title -
international journal of research in pharmaceutical chemistry and analysis
Language(s) - English
Resource type - Journals
ISSN - 2582-1970
DOI - 10.33974/ijrpca.v1i1.26
Subject(s) - thiazine , moiety , combinatorial chemistry , frame work , biological activity , chemistry , transformation (genetics) , ring (chemistry) , derivative (finance) , stereochemistry , organic chemistry , biochemistry , in vitro , engineering , business , architectural engineering , finance , gene
1,3 – Thiazines have been applied as useful starting materials in the stereo selective synthesis of compounds of pharmacological interest and they have served as chiral ligants and auxiliaries in enantioselective transformation. The thiazines are of great importance because they act as precursor for the synthesis of Cephalosporins (3,6-dihydro-2H-,1,3-thiazine) and then converted to the thiazine derivatives (an heterocyclic compounds). Therefore, it was thought to combine chalcones moiety to thiazine derivative together in a molecular frame work to see the biological activities, additive effort of these rings towards biological activities like Antibacterial and Antifungal activities.

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