Open AccessSynthesis and Characterization of Novel Thienylpyridazine Derivatives
Author(s) -
Sara Sofia Marques Fernandes,
M. Manuela M. Raposo
Publication year - 2014
Language(s) - English
Resource type - Conference proceedings
DOI - 10.3390/ecsoc-18-a016
Subject(s) - pyridazine , thiophene , suzuki reaction , chemistry , aryl , acceptor , combinatorial chemistry , materials science , stereochemistry , organic chemistry , physics , condensed matter physics , alkyl
We report the synthesis and the photophysical characterization of novel thienyl-pyridazine derivatives, functionalized in position 3, with different donor groups (thiophene, pyrrole and N,N-dialkylphenylamine). The diazines were synthesized by Suzuki coupling of 3-bromo-6-(thiophen-2-yl)pyridazine with commercially available (hetero)aryl-boronic acids in fair to good yields. On the other hand, precursor 3-bromo-6-(thiophen-2-yl)pyridazine was prepared by reaction of a thienyl-pyridazinone with POBr3.Fundação para a Ciência e a Tecnologia (FCT