Open AccessNovel synthesis of 3-fluoro- and 3,3-difluoro-substituted β-lactams: evaluation as potential antiproliferative and tubulin destabilizing agents
Author(s) -
Azizah M. Malebari,
Mary J. Meegan
Publication year - 2019
Publication title -
proceedings of 5th international electronic conference on medicinal chemistry
Language(s) - English
Resource type - Conference proceedings
DOI - 10.3390/ecmc2019-06303
Subject(s) - staudinger reaction , chemistry , stereochemistry , ring (chemistry) , imine , lactam , ketene , tubulin , beta lactam , combinatorial chemistry , reformatsky reaction , microtubule , medicinal chemistry , organic chemistry , catalysis , biology , microbiology and biotechnology , biochemistry , antibiotics