
Quantification of Antifibrillarin (anti-U3 RNP) Antibodies: A New Insight for Patients with Systemic Sclerosis
Author(s) -
A. Benyamine,
Daniel Bertin,
Noémie Resseguier,
Xavier Heim,
Julien Bermudez,
David Launay,
Sylvain Dubucquoi,
Adrian Hij,
D. Farge,
Alain Lescoat,
I. BahonRiedinger,
Nouria Benmostefa,
Luc Mouthon,
JeanRobert Harlé,
Gilles Kaplanski,
P. Rossi,
Nathalie Bardin,
B. Granel
Publication year - 2021
Publication title -
diagnostics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.622
H-Index - 19
ISSN - 2075-4418
DOI - 10.3390/diagnostics11061064
Subject(s) - iif , autoantibody , medicine , context (archaeology) , pathology , antibody , immunology , biology , paleontology
The detection of additional autoantibodies is of great concern in systemic sclerosis (SSc) when those included in the ACR/EULAR classification are negative. In this context, the interest of antifibrillarin (anti-U3RNP) autoantibodies (AFAs) in the routine evaluation of SSc remains unclear. We aimed to assess the relevance of AFAs and their clinical association in SSc patients.