Effects of Paracetamol in Non-Specific Immunological Parameters

Our study includes follow up the effect of excessive dose of paracetamol in some individuals on nonspecific immunological parameters, the study estimates total white blood cell count and calculates the absolute number of neutrophils, lymphocytes and monocytes in blood, and estimation of the effectiveness of phagocytic cells of neutrophils. The study included the collection of (30) blood samples from individuals used paracetamol with excessive dose with age range between (20-40) years of both sexes, blood samples individuals donors do not use paracetamol as control samples were used as well. The results showed no significant differences in number of total white blood cell count and number of lymphocytes for individuals with excessive dose of paracetamol compared with control, on another hand the results showed a significant increase in number of neutrophils and monocytes compared with control, concerning the phagocytic activity, the results showed a significant reduction in phagocytic activity in individuals with excessive dose of paracetamol compared with control.