Biochemical Bone Indices and Serum Uric Acid Changes in Postmenopausal Women

The objective of this study was to evaluate the effect of menopause on: body mass index (BMI), serum levels of total protein, albumin, globulin, total calcium, uric acid, activity of acid phosphatase (ACP) and tartarate-resistant acid phosphatase (TRACP 5b). The study involves 50 participants who were categorized into two groups; premenopausal women group (n=25) (age, 47.18 ±4.10 years) and postmenopausal women group (n=25) (age, 58.58 ±4.51years). In comparative evaluation, the serum total protein, calcium, uric acid, activity of ACP and TRACP 5b were found to be significantly increased (p<0.05) in post menopausal women as compared to premenopausal women. Postmenopausal women are exposed to a greater risk of serum biochemical changes as compared to the premenopausal women, thus leading to an increased risk of osteoporosis and cardiovascular diseases after menopause.