Role of Green Tea Extract in Reducing Pathological Changes of Induced Diabetes Mellitus in Rats | Zendy

Kamal Ahmed Khidir | Zendy; Sarmad Raheem Kareem | Zendy; Ismail S. Kakey | Zendy

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Role of Green Tea Extract in Reducing Pathological Changes of Induced Diabetes Mellitus in Rats

Author(s) -

Kamal Ahmed Khidir,

Sarmad Raheem Kareem,

Ismail S. Kakey

Publication year - 2013

Publication title -

mağallaẗ ʻulūm al-rāfidayn

Language(s) - English

Resource type - Journals

eISSN - 2664-2786

pISSN - 1608-9391

DOI - 10.33899/rjs.2013.77808

Subject(s) - diabetes mellitus , pathological , pancreas , green tea , medicine , alloxan , reversion , normal group , kidney , body weight , endocrinology , green tea extract , physiology , traditional medicine , biology , biochemistry , food science , gene , phenotype

Thirty male albino rats were used to investigate the effect of green tea extract on pancreas, renal and hepatic histological parameters in alloxan induced diabetes mellitus. The animals were randomly distributed into five groups of six animals in each group. The first group was regarded as normal healthy control, the second group was regarded as diabetic control, the third group was treated with insulin, the fourth group was treated with green tea extract, 50 mg/kg body weight (GTE50), and the fifth group was treated with GTE100. This study showed that functionally diabetes related organs such as pancreas, kidney and liver showed diabetes related pathological changes and these revealed a noticeable tendency for reversion to normal after treatment with green tea extract.

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