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Synthesis of some Fused Heterocyclic Compounds from α-Bromo Tetralone and Indanone
Author(s) -
Akram N. Mohammad,
Ahlam M.N. Yahya
Publication year - 2010
Publication title -
mağallaẗ ʻulūm al-rāfidayn
Language(s) - English
Resource type - Journals
eISSN - 2664-2786
pISSN - 1608-9391
DOI - 10.33899/rjs.2010.36837
Subject(s) - tetralone , chemistry , combinatorial chemistry , stereochemistry
A number of heterocyclic compounds (7-14) were prepared by the reaction of α- bromo ketones (3,4) with 2-amino-5-phenyl-1,3,4(thiadiazole or oxadiazole) and 5-phenyl- 1,3,4-triazole-2-thiol. Moreover, on heating under reflux of α-bromo ketones (3,4) in the presence of ethanol with thiazole derivatives (5,6) (was prepared from the reaction of α- bromo ketone (3,4) with thiourea), compounds (7,8) were obtained. The structure of the synthesized compounds have been elucidated by their physical and spectral methods .

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