Synthesis and Cyclization of some N-(2-Pyridyl) Anthranilic Acids | Zendy

Azam A. AL-Hadedi | Zendy; Rafid K. Jameel | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Synthesis and Cyclization of some N-(2-Pyridyl) Anthranilic Acids

Author(s) -

Azam A. AL-Hadedi,

Rafid K. Jameel

Publication year - 2010

Publication title -

mağallaẗ ʻulūm al-rāfidayn

Language(s) - English

Resource type - Journals

eISSN - 2664-2786

pISSN - 1608-9391

DOI - 10.33899/rjs.2010.36807

Subject(s) - chemistry , anthranilic acid , elemental analysis , chloride , thin layer chromatography , chromatography , medicinal chemistry , spectral analysis , organic chemistry , nuclear chemistry , physics , quantum mechanics , spectroscopy

A series of N-(2-Pyridyl) anthranilic acids (Ia-f) have been synthesized by Ullmann reaction. Cyclization of (Ib,d,f) by phosphorusoxy chloride (POCl3) gives substituted 5chlorobenzo [b][1,8] naphthyridine compounds. The reaction progress was followed by thin layer chromatography (TLC), rate flow (Rf) values was recorded, spectral data (IR) and (U.V) were recorded. Elemental analysis (CHNS) and gas chromatography-mass spectrometery (GC/MS) were carried out for some of the synthesized compounds.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research