Synthesis of some Acetylenic Amines Derivatives by Mannich Reaction
Author(s) -
Haiffaa Y. Hussin
Publication year - 2009
Publication title -
mağallaẗ ʻulūm al-rāfidayn
Language(s) - English
Resource type - Journals
eISSN - 2664-2786
pISSN - 1608-9391
DOI - 10.33899/rjs.2009.39942
Subject(s) - paraformaldehyde , mannich reaction , uracil , chemistry , cytosine , amine gas treating , mannich base , propargyl , organic chemistry , combinatorial chemistry , catalysis , dna , biochemistry
Some acetylenic amine derivatives containing nitrogen bases (cytosine, uracil) were synthesized through Mannich reaction which involved reaction of N-propargyl cytosine or uracil with paraformaldehyde and secondary amines. The structure of synthesized compounds have been confirmed depending on the physical and spectral data.
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