Efficacy of Paracetamol versus Celebrex on the Control of Post Operative Complications of Lower Third Molars

Aims: To compare the efficacy of celebrex 400 mg orally one time daily with paracatamol 1000 mg orally four times daily on reducing post operative oral complication (facial swelling, trismus and pain) after third molar surgery. Materials and Methods: A total of 45 patients (24 females, 21 males) with impacted lower third molars divided into two groups; Group I: Twenty patients treated with paracetamol 1000 mg orally four times daily. Group II: Twenty five patients treated with celebrex 400 mg orally one time daily. Results: The mean age of patients was (29.17 ± 5.0) in group I and (27.1± 4.9) in group II with no significant differences, with a higher percentage of mesioangular impaction 40% among other type of impaction in two groups. Patients in group II suffer from less facial swelling and trismus with a significant differences p ≤ 0.05 compared with group I, but the two groups showed no significant differences in related to pain (p> 0.05) after third molar's surgical removal. Conclusions: Celebrex is more effective than paracetamol with less frequency of administration and longer duration of action in reducing post operative oral complication (swelling and trismus), but with some analgesic effect after surgical removal of lower third molars.