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Synthesis of some Heterocyclic Compounds from 1,4-Benzoxazine-3-one
Author(s) -
Omar A. Salih
Publication year - 2013
Publication title -
mağallaẗ al-tarbiyaẗ wa-al-ʻilm
Language(s) - English
Resource type - Journals
eISSN - 2664-2530
pISSN - 1812-125X
DOI - 10.33899/edusj.2013.89662
Subject(s) - thioglycolic acid , chemistry , hydrazine (antidepressant) , hydrate , reagent , phenol , organic chemistry , chloride , ethyl acetate , ethyl ester , chromatography
The compound (1) was synthesized by reacting 2-amino phenol with ethyl bromo acetate.The treatment of ethyl bromo acetate with compound (1) gave (2), While compound (3) was produced by reacting hydrazine hydrate with compound (2). Compound (3) was used as precursor to prepare (4-12) by reacting it with different chemical reagents. The reaction of (11) with thioglycolic acid, 3-chloro perbenzoic acid afforded (13,14) respectively, while compound (15) was prepared from the reaction of (12) with chloro acetyl chloride. The products were identified by physical, chemical and spectroscopic methods.

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