Open AccessSpectrophotometric Assay of Dipyrone in Pharmaceutical Preparations Via Oxidative Coupling Reaction with
Author(s) -
Elham Salih,
M.M. Al-Sharook
Publication year - 2008
Publication title -
mağallaẗ al-tarbiyaẗ wa-al-ʻilm
Language(s) - English
Resource type - Journals
eISSN - 2664-2530
pISSN - 1812-125X
DOI - 10.33899/edusj.2008.51237
Subject(s) - molar absorptivity , oxidative coupling of methane , chemistry , chromatography , aqueous solution , potassium , color reaction , nuclear chemistry , organic chemistry , catalysis , physics , optics , reagent
A simple, rapid and highly sensitive spectrophotometric method has been described for the determination of dipyrone in a bulk and in dosage forms. The method depends on the organic oxidative coupling reaction of dipyrone with m-toluidine in the presence of potassium hexacyanoferrate (III) in aqueous solution to form purple product measured at 530 nm. Beer's law is obeyed in the concentration range 0.4- 10.0
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