English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

Binge drinking (BD) is characterized by high alcohol intake in a short time followed by periods of withdrawal. This pattern is very common during adolescence and early adulthood, a developmental stage marked by the maturation of the fronto-striatal networks. The basal ganglia, specifically the nucleus accumbens (NAcc) and the caudate nucleus (CN), are part of the fronto-striatal limbic circuit involved in reward processes underlying addictive behaviors. Abnormal NAcc and CN morphometry has been noted in alcoholics and other drug abusers, however the effects of BD on these subcortical regions have been poorly explored. Accordingly, the main goal of the present study was to address potential morphological alterations in the NAcc and CN in a sample of college binge drinkers (BDs).    Method  Manual segmentation of the NAcc and the CN was performed in Magnetic Resonance Imaging (MRI) of 20 college BDs and 16 age-matched alcohol abstainers (18–23 years-old).    Results  A two-way mixed ANOVA revealed no group differences in the volumetry of the CN, whereas increased NAcc volume was observed in the BD group when compared to their abstinent control peers.    Discussion  These findings are in line with previous automatically segmented MRI reports highlighting abnormalities in a key region involved in drug rewarding processes in BDs.

Increased Nucleus Accumbens Volume in College Binge Drinkers - Preliminary Evidence From Manually Segmented MRI Analysis