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Revisiting Risk Governance of GM Plants: The Need to Consider New and Emerging Gene-Editing Techniques
Author(s) -
Sarah Za Agapito-Tenfen,
Arinze S. Okoli,
Michael J. Bernstein,
Odd-Gunnar Wikmark,
Anne Ingeborg Myhr
Publication year - 2018
Publication title -
frontiers in plant science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.752
H-Index - 125
ISSN - 1664-462X
DOI - 10.3389/fpls.2018.01874
Subject(s) - genome editing , relevance (law) , corporate governance , value (mathematics) , process (computing) , product (mathematics) , emerging technologies , biology , microbiology and biotechnology , risk analysis (engineering) , genome , computer science , gene , business , political science , genetics , geometry , mathematics , finance , law , operating system , artificial intelligence , machine learning
New and emerging gene-editing techniques make it possible to target specific genes in species with greater speed and specificity than previously possible. Of major relevance for plant breeding, regulators and scientists are discussing how to regulate products developed using these gene-editing techniques. Such discussions include whether to adopt or adapt the current framework for GMO risk governance in evaluating the impacts of gene-edited plants, and derived products, on the environment, human and animal health and society. Product classification or definition is one of several aspects of the current framework being criticized. Further, knowledge gaps related to risk assessments of gene-edited organisms—for example of target and off-target effects of intervention in plant genomes—are also of concern. Resolving these and related aspects of the current framework will involve addressing many subjective, value-laden positions, for example how to specify protection goals through ecosystem service approaches. A process informed by responsible research and innovation practices, involving a broader community of people, organizations, experts, and interest groups, could help scientists, regulators, and other stakeholders address these complex, value-laden concerns related to gene-editing of plants with and for society.

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