Novel Treatments in Lupus | Zendy

Milena Vukelic | Zendy; Yi Li | Zendy; Vasileios C. Kyttaris | Zendy

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Novel Treatments in Lupus

Author(s) -

Milena Vukelic,

Yi Li,

Vasileios C. Kyttaris

Publication year - 2018

Publication title -

frontiers in immunology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.646

H-Index - 124

ISSN - 1664-3224

DOI - 10.3389/fimmu.2018.02658

Subject(s) - medicine , systemic lupus erythematosus , immunosuppression , clinical trial , monoclonal antibody , immunology , lupus erythematosus , antibody , disease

Purpose of Review: The standard treatment options for systemic lupus erythematosus (SLE) are focused on non-specific immunosuppression. Over the past few years, scientific studies and ongoing clinical trials have shifted the paradigm with rapid advances in developing biologics and small molecules. A number of monoclonal antibodies and small molecule inhibitors have been developed to target specific pathways involved in SLE. Many of these novel therapeutic agents are already being tested in clinical trials and they may 1 day reshape the landscape of SLE treatment. Herein we review potential future therapeutic options for SLE.

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