Advances in the Application of Supramolecular Hydrogels for Stem Cell Delivery and Cartilage Tissue Engineering | Zendy

Xin Yan | Zendy; YouRong Chen | Zendy; Yifan Song | Zendy; Jing Ye | Zendy; Meng Yang | Zendy; Bingbing Xu | Zendy; Jiying Zhang | Zendy; Xing Wang | Zendy; JiaKuo Yu | Zendy

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Advances in the Application of Supramolecular Hydrogels for Stem Cell Delivery and Cartilage Tissue Engineering

Author(s) -

Xin Yan,

YouRong Chen,

Yifan Song,

Jing Ye,

Meng Yang,

Bingbing Xu,

Jiying Zhang,

Xing Wang,

JiaKuo Yu

Publication year - 2020

Publication title -

frontiers in bioengineering and biotechnology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.081

H-Index - 44

ISSN - 2296-4185

DOI - 10.3389/fbioe.2020.00847

Subject(s) - self healing hydrogels , tissue engineering , cartilage , stem cell , regeneration (biology) , supramolecular chemistry , articular cartilage , biomedical engineering , nanotechnology , materials science , medicine , chemistry , anatomy , microbiology and biotechnology , pathology , biology , osteoarthritis , polymer chemistry , crystal structure , alternative medicine , crystallography

Cartilage defects pose a great threat to the health of the aging population. Cartilage has limited self-regeneration ability because it lacks blood vessels, nerves and lymph. To achieve efficient cartilage regeneration, supramolecular hydrogels are used in medical applications and tissue engineering as they are tunable and reversible in nature. Moreover, they possess supramolecular interactions which allow the incorporation of cells. These hydrogels present great potential for tissue engineering-based therapies. This review presents advances in the development of stem cell-laden supramolecular hydrogels. We discuss new possibilities for stem cell therapy and their uses in cartilage tissue engineering. Gray areas and future perspectives are discussed.

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