Open AccessSimultaneous Estimation of Metformin and Glimipride by Ultraviolet Spectrophotometry Using Absorbance Ratio Method.
Author(s) -
Suruse S.D .,
MIRANDA André T.B.
Publication year - 2012
Publication title -
journal of current pharma research
Language(s) - English
Resource type - Journals
eISSN - 2230-7842
pISSN - 2230-7834
DOI - 10.33786/jcpr.2012.v02i04.001
Subject(s) - absorbance , spectrophotometry , ultraviolet , metformin , chemistry , chromatography , materials science , medicine , insulin , optoelectronics
The simple, accurate, economical and reproducible spectrophotometric method for simultaneous estimation of two-component drug mixture of metformin and Glimipride in combined tablet dosage form has been developed. Developed method is based on direct estimation of metformin and Glimipride at 234nm and 232nm. For estimation absorbance ratio method was developed .The developed methods obey Beer's law in the concentration ranges 5-25μg/ml. The results of analysis were validated statistically.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom