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The dentist is often the first person who has the opportunity to detect mucosal alterations, such as ulcerations or white and red lesions in the oral cavity. Early diagnosis and proper management can prevent unfavorable outcomes in these patients. Indeed, chronic mucosal trauma resulting from sharp teeth and faulty restorations has been associated with the development of oral cancer [1]. The aim of these series of different ethnic cases is to present and focus on the clinical experiences from various cases in the Oral Medicine clinic at the Faculty of Dentistry, Chulalongkorn University and Bangkok, Thailand. This paper highlights the relationship between longstanding irritation, trauma, poor oral hygiene, old age, and oral cancer. Although not all the risk factors for developing oral squamous cell carcinoma (OSCC) have been determined, it is likely that malignant transformation has a multifactorial etiology [2-4]. Some of the oral manifestations of the cases presented here might explain the possible link to the pathogenesis of OSCC.

Chronic Oral Mucosal Trauma and Oral Cancer: A Series of Cases