Early Insights into COVID-19 in Persons Living with HIV and Cardiovascular Manifestations | Zendy

Jelani Grant | Zendy; Louis Vincent | Zendy; Bertrand Ebner | Zendy; Barry E. Hurwitz | Zendy; María L. Alcaide | Zendy; Claudia Martinez | Zendy

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Early Insights into COVID-19 in Persons Living with HIV and Cardiovascular Manifestations

Author(s) -

Jelani Grant,

Louis Vincent,

Bertrand Ebner,

Barry E. Hurwitz,

María L. Alcaide,

Claudia Martinez

Publication year - 2020

Publication title -

journal of aids and hiv treatment

Language(s) - English

Resource type - Journals

ISSN - 2688-7436

DOI - 10.33696/aids.2.010

Subject(s) - pandemic , medicine , covid-19 , context (archaeology) , human immunodeficiency virus (hiv) , virus , intensive care medicine , immunology , virology , disease , infectious disease (medical specialty) , biology , paleontology

Persons living with HIV-1 (PLHIV) are at increased risk of cardiovascular complications in part due to the persistent inflammatory state despite viral suppression. SARS-CoV-2, the virus causing COVID-19, was declared a pandemic virus in March 2020, and caused over 30 million cases and 900,000 deaths worldwide to date. Individuals with COVID-19 are manifesting acute cardiovascular complications because of the inflammatory response associated with SARS-CoV-2 infection. It is not yet known whether having COVID-19 in the context of ongoing HIV-1 infection results in worse cardiovascular complications than in PLHIV who have not had COVID-19 infection. In this review, the potential for exacerbated cardiovascular manifestations in persons coinfected with HIV-1 and COVID-19 is considered.

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