English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

Persons living with HIV/AIDS (PLWHA) are at higher risk of developing adverse cutaneous reactions compared to the general population [1,2]. Numerous antiretrovirals approved for HIV treatment are associated with adverse dermatological reactions such as non-nucleoside reverse transcriptase inhibitors, protease inhibitors (specifically darunavir and amprenavir), and the CD4 T-lymphocyte attachment inhibitor ibalizumab [3]. Some antiretrovirals are associated with hypersensitivity reaction, one example is PLWHA who test positive for HLA-B*5701 allele and are prescribed the nucleoside reverse transcriptase inhibitor abacavir. This type of reaction is characterized by rash, fever, malaise, and flu-like illness and is the reason why all patients should receive HLA-B*5701 screening before initiating abacavir [4]. A few antiretrovirals (nevirapine and raltegravir) have been reported to cause drug rash with eosinophilia and systemic symptoms (DRESS), nevirapine has also been associated with Stevens-Johnson Syndrome and toxic epidermal necrolysis [5-7]. These reactions can be life-threatening, but are uncommon, and typically appear days to weeks after initiation of the triggering drug. Another potentially life-threatening adverse drug reaction is anaphylaxis, which is rarely associated with antiretrovirals, only a few cases have been reported in the literature [8,9].

Anaphylaxis Drug Reaction after Initiation of Bictegravir