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Prucalopride: the evidence for its use in the treatment of chronic constipation.
Author(s) -
Georges Coremans
Publication year - 2008
Publication title -
pubmed
Language(s) - English
Resource type - Journals
ISSN - 1555-175X
DOI - 10.3355/ce.2008.011
Subject(s) - medicine , chronic constipation , constipation , adverse effect , intensive care medicine , quality of life (healthcare) , enema , stimulant , nursing
Chronic constipation is a common condition that is difficult to treat. Existing options for the treatment of patients with different subgroups of constipation are limited. A new efficacious and safe drug is needed to limit the frequently observed adverse effects induced by laxatives, to improve general wellbeing and quality of life, and to provide an alternative for enemas or even resectional surgery in patients in whom stimulant laxatives cause disabling adverse effects or fail to increase bowel movement frequency.

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