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I have read with interest the study by Yoo et al.,1 on the “Genetic Contributions to Childhood Obesity: Association of Candidate Gene Polymorphisms and Overweight/Obesity in Korean Preschool Children.” The authors reported that their data suggest that overweight children exhibited a higher frequency of the A allele in the AT2 C3123A polymorphism compared to the controls (odds ratio [OR], 1.72; 95% confidence interval [CI], 1.03–2.88; P = 0.038), and the frequency of C allele in the transforming growth factor beta-1 (TGF-β1, OMIM: 190180) T869C polymorphism (OR, 1.93; 95% CI, 1.15–3.21; P = 0.010) was also higher in obese or overweight children than in control subjects.1

journal of korean medical science/journal of korean medical science

Letter to the Editor: Genetic Contributions to Childhood Obesity: Association of Candidate Gene Polymorphisms and Overweight/Obesity in Korean Preschool Children