ArmAandRmtBWere the Predominant 16S RMTase Genes Responsible for Aminoglycoside-resistant Isolates in Korea | Zendy

Tae Hee Lee | Zendy; JooHee Hwang | Zendy; WooKon Lee | Zendy; MinKyoung Shin | Zendy; Hye Ryun Woo | Zendy; Kyung Min Chung | Zendy; ChangSeop Lee | Zendy

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ArmAandRmtBWere the Predominant 16S RMTase Genes Responsible for Aminoglycoside-resistant Isolates in Korea

Author(s) -

Tae Hee Lee,

JooHee Hwang,

WooKon Lee,

MinKyoung Shin,

Hye Ryun Woo,

Kyung Min Chung,

ChangSeop Lee

Publication year - 2018

Publication title -

journal of korean medical science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.743

H-Index - 66

eISSN - 1598-6357

pISSN - 1011-8934

DOI - 10.3346/jkms.2018.33.e262

Subject(s) - amikacin , aminoglycoside , 16s ribosomal rna , biology , microbiology and biotechnology , gene , gram , ribosomal rna , genetics , antibiotics , bacteria

Pathogenic gram-negatives that produce 16S ribosomal RNA methyltransferases (16S RMTases) have already been distributed all over the world. To investigate the predominance of aminoglycoside resistance associated with 16S RMTases in Korea, we collected a total of 222 amikacin resistant Gram-negative clinical isolates from patient specimens between 1999 and 2015 from three hospital banks across Korea. and were the predominant 16S RMTase genes responsible for aminoglycoside-resistant isolates circulating in Korean community settings although only one -producing isolate was detected in 2006.

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