Development of Multiple Pigmented Nevi Within Segmental Nevus Depigmentosus | Zendy

Joo Hyun Shim | Zendy; Seong Jun Seo | Zendy; Kye Yong Song | Zendy; Chang Kwun Hong | Zendy

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Development of Multiple Pigmented Nevi Within Segmental Nevus Depigmentosus

Author(s) -

Joo Hyun Shim,

Seong Jun Seo,

Kye Yong Song,

Chang Kwun Hong

Publication year - 2002

Publication title -

journal of korean medical science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.743

H-Index - 66

eISSN - 1598-6357

pISSN - 1011-8934

DOI - 10.3346/jkms.2002.17.1.133

Subject(s) - nevus , dermatology , medicine , dysplastic nevus , lesion , blue nevus , spitz nevus , melanocytic nevus , pigmentation disorder , pathology , melanoma , cancer research

Nevus depigmentosus is a stable and well-circumscribed congenital hypomelanosis that may be in an isolated, dermatomal or systemic form. An 18-yr-old Korean man with segmental nevus depigmentosus developed multiple pigmented nevi which were present only within the confines of the leukoderma. Histologic and electron microscopic studies rendered a diagnosis of nevus depigmentosus with dysplastic nevus to the patient. The genetic alteration of melanocytes in the hypopigmented lesion is assumed to have resulted in the development of multiple pigmented nevi.

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