Clinical features and outcome of SIL/TAL1-positive T-cell acute lymphoblastic leukemia in children and adolescents: a 10-year experience of the AIEOP group | Zendy

Magali D'Angio | Zendy; Maria Grazia Valsecchi | Zendy; A. M. Testi | Zendy; Valentino Conter | Zendy; Vinícius Santaunes | Zendy; Rosanna Parasole | Zendy; Antonella Colombini | Zendy; Nicola Santoro | Zendy; Stefania Varotto | Zendy; Michael Caniglia | Zendy; D. Silvestri | Zendy; Caterina Consarino | Zendy; Lauretta Levati | Zendy; Elisa Magrin | Zendy; Franco Locatelli | Zendy; Giuseppe Basso | Zendy; Robin Foà | Zendy; Andrea Biondi | Zendy; Giovanni Cazzaniga | Zendy

Open Access

Clinical features and outcome of SIL/TAL1-positive T-cell acute lymphoblastic leukemia in children and adolescents: a 10-year experience of the AIEOP group

Author(s) -

Magali D'Angio,

Maria Grazia Valsecchi,

A. M. Testi,

Valentino Conter,

Vinícius Santaunes,

Rosanna Parasole,

Antonella Colombini,

Nicola Santoro,

Stefania Varotto,

Michael Caniglia,

D. Silvestri,

Caterina Consarino,

Lauretta Levati,

Elisa Magrin,

Franco Locatelli,

Giuseppe Basso,

Robin Foà,

Andrea Biondi,

Giovanni Cazzaniga

Publication year - 2014

Publication title -

haematologica

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.782

H-Index - 142

eISSN - 1592-8721

pISSN - 0390-6078

DOI - 10.3324/haematol.2014.112151

Subject(s) - lymphoblastic leukemia , medicine , pediatrics , leukemia , gerontology

T-cell acute lymphoblastic leukemia (T-ALL) accounts for approximately 15% and 25% of childhood and adult cases of ALL, respectively,1,2 and is associated with a less favorable outcome.1 In recent years, however, more intensive and risk-adapted treatment has significantly improved the outcome of patients with T-ALL, leading to cure rates approaching 70% in children and adolescents, and 30%-40% in adults.2–4

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