Open AccessTowards rational graft-versus-host disease prophylaxis
Author(s) -
Christoph Bucher,
Jakob Passweg
Publication year - 2012
Publication title -
haematologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.782
H-Index - 142
eISSN - 1592-8721
pISSN - 0390-6078
DOI - 10.3324/haematol.2012.080226
Subject(s) - calcineurin , medicine , graft versus host disease , host (biology) , disease , transplantation , bone marrow transplantation , immunology , surgery , biology , ecology
Calcineurin inhibition for graft -versus -host disease (GvHD) prophylaxis was introduced into clinical practice of bone marrow transplantation about 35 years ago. Through the early work of Storb, Deeg and Ringden it became clear that calcineurin inhibition with cyclosporine A as a single agent was
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