High Angiotensin II Responsiveness is Associated with Decreased Endothelium-Dependent Relaxation in Human Arteries
Author(s) -
Adriaan A. Voors,
Peter Paul van Geel,
Hendrik Buikema,
Margreeth Oosterga,
Dirk J. van Veldhuisen,
Wiek H. van Gilst
Publication year - 2005
Publication title -
journal of the renin-angiotensin-aldosterone system
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.457
H-Index - 46
eISSN - 1752-8976
pISSN - 1470-3203
DOI - 10.3317/jraas.2005.021
Subject(s) - phenylephrine , angiotensin ii , medicine , endocrinology , endothelium , contraction (grammar) , artery , angiotensin converting enzyme , coronary artery disease , coronary arteries , renin–angiotensin system , chemistry , receptor , blood pressure
Animal studies demonstrated an interaction between angiotensin II (Ang II) responsiveness and endothelium-dependent relaxation (EDR). However, this relation has not been well described in humans. Therefore, we investigated the relation between Ang II responsiveness and EDR in isolated human arteries.
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