Pneumococcal Meningitis Among Children in the Post-13-Valent Pneumococcal Conjugate Vaccine Era: Three Case Reports

Acute bacterial meningitis is a serious disease and a medical emergency with a high rate of mortality and risk of neurological sequels, especially among young children [1, 2]. Additionally, the disease can have negative impacts on cerebral blood perfusion, resulting in hypoxia and cell death. It requires an efficient therapy that may rapidly sterilize the central nervous system and limit the inflammatory response [3]. Furthermore, the mortality rate attributed to pneumococcal meningitis is significantly higher (30%) compared to meningococcal meningitis (7%) [1].