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Oral versus intravenous antibiotics for bone and joint infections: the OVIVA non-inferiority RCT
Author(s) -
Matthew Scarborough,
Ho Kwong Li,
Ines Rombach,
Rhea Zambellas,
A. Sarah Walker,
Martin McNally,
Bridget L. Atkins,
Michelle Kümin,
Benjamin A. Lipsky,
Harriet Hughes,
Deepa Bose,
Simon Warren,
Damien Mack,
Jonathan Folb,
Elinor Moore,
Neil Jenkins,
Susan Hopkins,
R.A. Seaton,
Carolyn Hemsley,
Jonathan Sandoe,
Ila Aggarwal,
Simon Ellis,
Rebecca Sutherland,
Claudia Geue,
Nicola McMeekin,
Claire Scarborough,
John R. Paul,
Graham Cooke,
Jennifer Bostock,
Elham Khatamzas,
Nick Wong,
Andrew Brent,
José Manuel Lomas,
Philippa C. Matthews,
Tri Wangrangsimakul,
Roger Gundle,
Mark Rogers,
Adrian Taylor,
Guy Thwaites,
Philip Bejon
Publication year - 2019
Publication title -
health technology assessment
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.426
H-Index - 126
eISSN - 2046-4924
pISSN - 1366-5278
DOI - 10.3310/hta23380
Subject(s) - medicine , randomized controlled trial , antibiotics , clinical endpoint , quality of life (healthcare) , physical therapy , surgery , nursing , microbiology and biotechnology , biology
Management of bone and joint infection commonly includes 4-6 weeks of intravenous (IV) antibiotics, but there is little evidence to suggest that oral (PO) therapy results in worse outcomes.

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