Adjunctive rifampicin to reduce early mortality from Staphylococcus aureus bacteraemia: the ARREST RCT | Zendy

Guy Thwaites | Zendy; Matthew Scarborough | Zendy; Alexander J. Szubert | Zendy; Pedro Saramago | Zendy; Marta Soares | Zendy; Jennifer Bostock | Zendy; Emmanuel Nsutebu | Zendy; Robert Tilley | Zendy; Richard Cunningham | Zendy; Julia Greig | Zendy; Sarah Wyllie | Zendy; Peter Wilson | Zendy; Cressida Auckland | Zendy; Janet Cairns | Zendy; Denise Ward | Zendy; Pankaj Lal | Zendy; Achyut Guleri | Zendy; Neil Jenkins | Zendy; Julian Sutton | Zendy; Martin Wiselka | Zendy; Armando González-Ruiz | Zendy; Clive Graham | Zendy; Paul Chadwick | Zendy; Gavin Barlow | Zendy; N Claire Gordon | Zendy; Bernadette C. Young | Zendy; Sarah Meisner | Zendy; Paul McWhinney | Zendy; David A Price | Zendy; David Harvey | Zendy; Deepa Nayar | Zendy; Dakshika Jeyaratnam | Zendy; Tim Planche | Zendy; Jane Minton | Zendy; Fleur Hudson | Zendy; Susan Hopkins | Zendy; John Williams | Zendy; M. Estée Török | Zendy; Martin Llewelyn | Zendy; Jonathan D. Edgeworth | Zendy; A. Sarah Walker | Zendy

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Adjunctive rifampicin to reduce early mortality from Staphylococcus aureus bacteraemia: the ARREST RCT

Author(s) -

Guy Thwaites,

Matthew Scarborough,

Alexander J. Szubert,

Pedro Saramago,

Marta Soares,

Jennifer Bostock,

Emmanuel Nsutebu,

Robert Tilley,

Richard Cunningham,

Julia Greig,

Sarah Wyllie,

Peter Wilson,

Cressida Auckland,

Janet Cairns,

Denise Ward,

Pankaj Lal,

Achyut Guleri,

Neil Jenkins,

Julian Sutton,

Martin Wiselka,

Armando González-Ruiz,

Clive Graham,

Paul Chadwick,

Gavin Barlow,

N Claire Gordon,

Bernadette C. Young,

Sarah Meisner,

Paul McWhinney,

David A Price,

David Harvey,

Deepa Nayar,

Dakshika Jeyaratnam,

Tim Planche,

Jane Minton,

Fleur Hudson,

Susan Hopkins,

John Williams,

M. Estée Török,

Martin Llewelyn,

Jonathan D. Edgeworth,

A. Sarah Walker

Publication year - 2018

Publication title -

health technology assessment

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.426

H-Index - 126

eISSN - 2046-4924

pISSN - 1366-5278

DOI - 10.3310/hta22590

Subject(s) - medicine , rifampicin , interquartile range , placebo , adjunctive treatment , randomized controlled trial , methicillin resistant staphylococcus aureus , surgery , staphylococcus aureus , tuberculosis , pathology , alternative medicine , biology , bacteria , genetics

Staphylococcus aureus bacteraemia is a common and frequently fatal infection. Adjunctive rifampicin may enhance early S. aureus killing, sterilise infected foci and blood faster, and thereby reduce the risk of dissemination, metastatic infection and death.

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