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Introduccion: el ependimoma mixopapilar (EM) es un tumor glial ependimario que afecta predominantemente a los adultos jovenes, se origina en el filum terminale, la cauda equina y el cono medular. Caso clinico: se presenta el caso de una paciente en quien durante el estudio de un dolor radicular se logra detectar ependimoma mixopapilar gigante, el cual comprometia gran parte del hueso sacro, mostrando un comportamiento localmente agresivo con intensa osteolisis. Conclusion: se discutieron las posibles teorias que explican la presencia de estos tumores a nivel sacro, en especial la presencia de remanentes embrionarios de tejido ependimario en los niveles mas caudales del canal vertebral y los posibles mecanismos que explican el comportamiento agresivo de estos tumores histologicamente benignos. Rev.cienc.biomed. 2015;6(2):348-353 PALABRAS CLAVE Columna vertebral; Ependimoma mixopapilar; Neoplasia extradural; Sacro; Region sacrococcigea. SUMMARY Introduction: myxopapillary ependymoma (MP) is a glial ependymal tumor that mainly affects young adults. The tumor originates in the filum terminale, the cauda equina and the conus medullaris. Case record: the case presented in a patient in whom a giant myxopapillary ependymoma was detected during a medical checkup for root pain. The tumor involved the sacral bones showing a locally aggressive behavior with intense osteolysis. Conclusion: possible theories that explain the presence of these tumors in sacral bones were discussed, focusing in the presence of embryonic remnants of ependymal tissue in the most caudal levels of the spinal canal, and the possible mechanisms that explain the aggressive behavior of these histologically benign tumors. Rev.cienc.biomed.2015; 6(2):348-353 KEYWORDS Spine; Myxopapillary ependymoma; Epidural neoplasm; Sacrum;Sacrococcygeal region.

Ependimoma mixopapilar osteolítico gigante del sacro: una forma agresiva de un tumor benigno