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The reduction of the organic matter concentration of hospital wastewater is expressed in BOD 5 and COD. The treatment was developed using a micro-nanobubble generator with continuous system. Micro-nanobubbles of 0.024μm average diameter were obtained. For the treatment, two samples were taken; Sample 1 (at 8:00 a.m.) and show 2 (at 11:00 a.m.). After applying the treatment with ozone-air micro-nanobubbles, it was possible to reduce the initial concentrations of sample 1: BOD 5 from 132mg/L to 14mg/L, COD from 374mg/L to 30mg/L and from sample 2: BOD 5 from 127mg/L to 21mg/L and COD from 297mg/L to 36mg/L. The efficiency obtained at 15 minutes of sample 1 of BOD 5 was 90.2% and of COD was 92.51% and of sample 2 of BOD 5 was 83.5% and of COD was 87.9%.

Reduction of hospital wastewater through ozone-air micro-nanobubbles