Open AccessA Case Report of Hutchinson-Gilford Progeria Syndrome
Author(s) -
Siamak Yaghoubi,
Sareh Mohammadi,
leili Dr.yekefallah,
Alireza Taromiha,
Ameneh Bagheri
Publication year - 2019
Publication title -
the journal of qazvin university of medical sciences
Language(s) - English
Resource type - Journals
eISSN - 2228-7213
pISSN - 1561-3666
DOI - 10.32598/jqums.23.1.84
Subject(s) - progeria , medicine , premature aging , disease , pediatrics , stroke (engine) , myocardial infarction , lmna , cardiology , genetics , physiology , gene , psychiatry , biology , mechanical engineering , lamin , nucleus , engineering
Hutchinson-Gilford Progeria Syndrome (HGPS), a rare genetic condition occurs one in every 8 million live births. HGPS is characterized by premature aging in various organs. The average survival rate of the affected patients is 13 years, and their most common causes of death are myocardial infarction and stroke. This disease occurs due to a gene mutation in the chromosomes of the patient. There is no definitive treatment for progeria, and most patients die at the age of 8 to 10 years. Scientists are interested in identifying this syndrome, as it may reveal the signs of a natural aging process at an early age. The studied patient was older than the global average with no cardiovascular disease and suffered from appendicitis.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom