PROFILE OF BLADDER TRANSITIONAL CELL CANCER IN SOETOMO HOSPITAL SURABAYA

Objectives : To describe the characteristic of bladder transitional cell cancer (TCC). M aterial & m ethods : We reviewed the medical records of patients with bladder TCC admitted in Soetomo General Hospital Surabaya , from January 2008 until December 2012. The data regarding demographic characteristics, clinical presentation and stagin g , grading and staging based on pathological examinations results, and the management of the cancer. Results : The 1 26 cases , consisted of 102 men (81%) and 24 women (19%) with its ratio was 4 . 2 : 1. All male patients were heavy cigarette smokers. M ean age was 57 . 8 years , peak incidence was 50-59 years. H ematuria was the most frequent clinical presentation (112 patients, 88 . 9%), urinary retention and other complaints (12 patients, 9 . 5%), and chronic dysuria (2 patients, 1 . 6%). C linical staging was T1 as NMIBC in 7 patients (5 . 7%). MIBC consisted of T2 in 37 patients (30 . 3%), T3 in 35 patients (28 . 7%), T4 in 43 patients (35 . 2%). The pathological grading as an high-grade were 74 patients (64 . 3%). All patients had underwent TURBT for diagnosis and staging, followed by definitive treatment. It consisted of TURBT and chemotherapy bladder instillation in 7 patients (5 . 6%), radical cystectomy in 13 patients (10 . 3%), EBRT in 5 patients (4%), MVAC chemotherapy in 24 patients (19%), EBRT and chemotherapy with MVAC in 3 patients (2 . 4%). There were 74 patients (58 . 7%) underwent TURBT alone. Conclusion : B ladder TCC was in advanced stage when diagnosed , most of the patients received only TURBT and refused further treatment. Keywords: Bladder transitional cell cancer, characteristics, managements . Normal 0 false false false EN-US X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin-top:0cm; mso-para-margin-right:0cm; mso-para-margin-bottom:10.0pt; mso-para-margin-left:0cm; line-height:115%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-ansi-language:IN;}