Repetitive Motor Control Deficits Most Consistent Predictors of Conversion to Freezing of Gait in Parkinson’s Disease: A Prospective Cohort Study | Zendy

Nicholas D’Cruz | Zendy; Griet Vervoort | Zendy; Steffen Fieuws | Zendy; Caroline Moreau | Zendy; Wim Vandenberghe | Zendy; Alice Nieuwboer | Zendy

Open Access

Repetitive Motor Control Deficits Most Consistent Predictors of Conversion to Freezing of Gait in Parkinson’s Disease: A Prospective Cohort Study

Author(s) -

Nicholas D’Cruz,

Griet Vervoort,

Steffen Fieuws,

Caroline Moreau,

Wim Vandenberghe,

Alice Nieuwboer

Publication year - 2020

Publication title -

journal of parkinson s disease

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.747

H-Index - 45

eISSN - 1877-718X

pISSN - 1877-7171

DOI - 10.3233/jpd-191759

Subject(s) - parkinson's disease , gait , physical medicine and rehabilitation , medicine , cohort , motor control , prospective cohort study , disease , psychology , psychiatry

The onset of freezing of gait (FOG) represents a turning point in the lives of patients with Parkinson's disease (PD). FOG increases fall risk and is associated with worse physical and mental health related quality of life, thus increasing disease burden. Moreover, therapeutic studies aiming to ameliorate freezing have had limited success. In a step towards pre-emptive therapy to delay or prevent the onset of FOG, this prospective cohort study set out to uncover clinical markers of conversion to FOG.

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