Open AccessSystemic Exposure to Lipopolysaccharide from Porphyromonas gingivalis Induces Bone Loss-Correlated Alzheimer’s Disease-Like Pathologies in Middle-Aged Mice
Author(s) -
Yebo Gu,
Zhou Wu,
Fan Zeng,
Muzhou Jiang,
Jessica L. Teeling,
Junjun Ni,
Ichiro Takahashi
Publication year - 2020
Publication title -
journal of alzheimer s disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.677
H-Index - 139
eISSN - 1875-8908
pISSN - 1387-2877
DOI - 10.3233/jad-200689
Subject(s) - porphyromonas gingivalis , microglia , lipopolysaccharide , periodontitis , neuroinflammation , inflammation , medicine , exacerbation , endocrinology , systemic inflammation , immunology , chemistry
Alzheimer's disease (AD) and bone loss are clinically exacerbated. However, the mechanism of exacerbation remains understood.
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