Effects of Chronic Masitinib Treatment in APPswe/PSEN1dE9 Transgenic Mice Modeling Alzheimer’s Disease | Zendy

Tengfei Li | Zendy; Elodie Martin | Zendy; Yah-se K. Abada | Zendy; Céline Boucher | Zendy; Aurélia Cès | Zendy; Ihsen Youssef | Zendy; Grégory Fenaux | Zendy; Yona Forand | Zendy; A. Legrand | Zendy; Nadkarni Nachiket | Zendy; Marc Dhénain | Zendy; Olivier Hermine | Zendy; Patrice Dubreuil | Zendy; Cécile Delarasse | Zendy; Benoı̂t Delatour | Zendy

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Effects of Chronic Masitinib Treatment in APPswe/PSEN1dE9 Transgenic Mice Modeling Alzheimer’s Disease

Author(s) -

Tengfei Li,

Elodie Martin,

Yah-se K. Abada,

Céline Boucher,

Aurélia Cès,

Ihsen Youssef,

Grégory Fenaux,

Yona Forand,

A. Legrand,

Nadkarni Nachiket,

Marc Dhénain,

Olivier Hermine,

Patrice Dubreuil,

Cécile Delarasse,

Benoı̂t Delatour

Publication year - 2020

Publication title -

journal of alzheimer s disease

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.677

H-Index - 139

eISSN - 1875-8908

pISSN - 1387-2877

DOI - 10.3233/jad-200466

Subject(s) - neuroinflammation , medicine , genetically modified mouse , alzheimer's disease , pharmacology , transgene , disease , endocrinology , chemistry , biochemistry , gene

Masitinib is a selective tyrosine kinase inhibitor that modulates mast cells activity. A previous phase II study reported a cognitive effect of masitinib in patients with Alzheimer's disease.

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