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Prediction of Mild Cognitive Impairment that Evolves into Alzheimer's Disease Dementia within Two Years using a Gene Expression Signature in Blood: A Pilot Study
Author(s) -
Line Roed,
Gisle Grave,
Torbjørn Lindahl,
Edith Rian,
Peter Otto Horndalsveen,
Lars Lannfelt,
Christer Nilsson,
Frank Swenson,
Anders Lönneborg,
Praveen Sharma,
Magnus Sjögren
Publication year - 2013
Publication title -
journal of alzheimer s disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.677
H-Index - 139
eISSN - 1875-8908
pISSN - 1387-2877
DOI - 10.3233/jad-122404
Subject(s) - dementia , disease , cognitive impairment , alzheimer's disease , expression (computer science) , medicine , cognition , prodromal stage , psychology , psychiatry , computer science , programming language
The focus on Alzheimer's disease (AD) is shifting from dementia to the prodromal stage of the disorder, to a large extent due to increasing efforts in trying to develop disease modifying treatment for the disorder. For development of disease-modifying drugs, a reliable and accurate test for identification of mild cognitive impairment (MCI) due to AD is essential.

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