Osteoblast differentiation and disinfection induced by nitrogen plasma-treated surfaces | Zendy

Wei Zhang | Zendy; Huaiyu Wang | Zendy; Ayako Oyane | Zendy; Hideo Tsurushima | Zendy; Paul K. Chu | Zendy

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Osteoblast differentiation and disinfection induced by nitrogen plasma-treated surfaces

Author(s) -

Wei Zhang,

Huaiyu Wang,

Ayako Oyane,

Hideo Tsurushima,

Paul K. Chu

Publication year - 2011

Publication title -

bio-medical materials and engineering

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.372

H-Index - 53

eISSN - 1878-3619

pISSN - 0959-2989

DOI - 10.3233/bme-2011-0657

Subject(s) - plasma immersion ion implantation , osteoblast , polymer , chemistry , surface engineering , surface modification , nitrogen , biophysics , nanotechnology , biomedical engineering , materials science , chemical engineering , ion implantation , ion , biochemistry , in vitro , organic chemistry , biology , medicine , engineering

Plasma technology is widely employed to tailor the surface chemistry of polymeric biomaterials. In this work, nitrogen-containing functional groups were generated on a polymer surface by N₂ plasma immersion ion implantation (PIII). We evaluated the abilities of the resulting surface to inhibit bacterial growth and to enhance osteoblast differentiation from the perspective of bone tissue engineering. Our results demonstrate that the N₂ PIII-treated polymer surface exhibits antibacterial properties against Escherichia coli. Moreover, the N₂ PIII-treated polymer surface has the ability to enhance differentiation of osteoblasts. N₂ PIII-treated polymer surface may therefore be useful in bone tissue engineering.

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