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Molecular Differentiation ofMycobacterium tuberculosisStrains without IS6110Insertions
Author(s) -
Kerry H. Lok,
William H. Benjamin,
Michael E. Kimerling,
Virginia Pruitt,
Monica J. Lathan,
Jafar Razeq,
Nancy Hooper,
Wendy Cronin,
Nancy E. Dunlap
Publication year - 2002
Publication title -
emerging infectious diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.54
H-Index - 226
eISSN - 1080-6059
pISSN - 1080-6040
DOI - 10.3201/eid0811.020291
Subject(s) - genotyping , mycobacterium tuberculosis , tuberculosis , genotype , restriction fragment length polymorphism , biology , virology , molecular epidemiology , dna profiling , genetics , microbiology and biotechnology , medicine , dna , gene , pathology
By using standard restriction fragment length polymorphism, 6 zero-copy IS6110 Mycobacterium tuberculosis isolates were identified from 1180 Maryland isolates as part of the National Tuberculosis Genotyping and Surveillance Network Project. By using various genotyping methods, we demonstrated that this zero band cluster can be differentiated into six genotypes.

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