Conjugate Vaccines and the Carriage of Haemophilus influenzae Type b | Zendy

M. L. Barbour | Zendy; D. Phil | Zendy

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Conjugate Vaccines and the Carriage of Haemophilus influenzae Type b

Author(s) -

M. L. Barbour,

D. Phil

Publication year - 1996

Publication title -

emerging infectious diseases

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.54

H-Index - 226

eISSN - 1080-6059

pISSN - 1080-6040

DOI - 10.3201/eid0203.960303

Subject(s) - carriage , conjugate vaccine , vaccination , haemophilus influenzae , conjugate , virology , pasteurellaceae , hib vaccine , microbiology and biotechnology , medicine , transmission (telecommunications) , haemophilus , immunology , biology , immunization , bacteria , antigen , antibiotics , genetics , mathematical analysis , mathematics , electrical engineering , pathology , engineering

Pharyngeal carriage of Haemophilus influenzae type b (Hib) is important in the transmission of Hib organisms, the pathogenesis of Hib disease, and the development of immunity to the bacterium. The remarkable success of current vaccination programs against Hib has been due in part to the effect of conjugate Hib vaccines in decreasing carriage of Hib. This review explores evidence for this effect, and discusses the possible mechanisms of the mucosal influence of Hib conjugate vaccines.

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