SYNTHESIS, ANTIOXIDANT AND ANTICANCER ACTIVITY OF NEW QUINOLINE-[1, 2, 4]-TRIAZOLE HYBRIDS | Zendy

Hemant Hegde | Zendy; Santosh L. Gaonkar | Zendy; Naveen P. Badiger | Zendy; Nitinkumar S. Shetty | Zendy

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SYNTHESIS, ANTIOXIDANT AND ANTICANCER ACTIVITY OF NEW QUINOLINE-[1, 2, 4]-TRIAZOLE HYBRIDS

Author(s) -

Hemant Hegde,

Santosh L. Gaonkar,

Naveen P. Badiger,

Nitinkumar S. Shetty

Publication year - 2020

Publication title -

rasayan journal of chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.281

H-Index - 22

eISSN - 0976-0083

pISSN - 0974-1496

DOI - 10.31788/rjc.2020.1335669

Subject(s) - quinoline , antioxidant , triazole , hybrid , chemistry , combinatorial chemistry , biochemistry , biology , organic chemistry , botany

A set of quinoline coupled triazole derivatives was synthesized using substituted quinoline hydrazide and isothiocyanate derivatives. The structures of the synthesized molecules were confirmed using spectral techniques like FTIR, 1H & 13C NMR spectroscopy. Novel triazole thione derivatives were subjected to anticancer and antioxidant activity. The studies revealed the moderate anticancer activity of the molecules but have shown potent antioxidant activity.

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