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The synthetic drugs for DM treatment are available in the market, but they have side effects in long term treatment. This makes a research about effective natural resources to reduce diabetes intensity are rampant, one of them is Coriander leaf (Coriandrum sativum L). Ethanolic extract of coriander leaf (EECL) was tested for phytochemical screening and anti-diabetic activity, by glucose tolerance test in normal rats and alloxan-induced diabetic mice. The mice were divided into five groups of six animals each (diabetic control, standard drug-treated, and plant treated groups (100, 20 and 400 mg/kg bw)). On the 0 th , 3 th , 6 th , 9 th , 12 th and 15 th days, the blood samples were analyzed for blood glucose.The results of phytochemical screening showed that EELC has a lot of phytochemical compounds such as alkaloids, flavonoids, tannins, glycosides, saponins and steroids. Antihyperglycemic study showed that there were not have significant differences between EECL and metformin 65 mg/kg bw group. Based on the research investigation, it can be concluded that EELChas an antihyperglicemia effect.

PHYTOCHEMICAL SCREENING AND ANTIHYPERGLYCEMIC ACTIVITY OF ETHANOLIC EXTRACT OF Coriandrum sativum L. LEAF