ANTIBACTERIAL ACTIVITY AND GREENER METHOD OF SYNTHESIS OF HETEROCYCLIC COMPOUNDS INCORPORATING BENZOTHIAZOLE MOIETY USING IONIC LIQUID AS SOLVENT

A novel series of 2-amino-6-substituted benzothiazoles with halo esters and halo ketones have been synthesized by a conventional method. The same series was also synthesized under Microwave condition using ionic liquids. The yield of products by Microwave synthesis with ionic liquids is much better than the conventional method and also save time and energy. All the reported compounds in this article have been characterized by IR, 1 H NMR data and elemental analysis in full accordance with their expected (depicted) structures. The reported compounds were further screened for their antibacterial activity using Ampicillin as standard drug. The compounds showed excellent activity against bacteria Pseudomonas Aeruginosa, Klebsiella pneumonia and Staphylococcus aureus.