STUDIES ON POST HETEROCYCLIZATION OF 1, 3, 4- OXADIAZOLE CONTAINING AZETIDINONES DERIVATIVES AND THEIR BIOLOGICAL STUDIES
Author(s) -
Jayesh M. Pandya,
Jyotindra Mahyavanshi
Publication year - 2019
Publication title -
rasayan journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.281
H-Index - 22
eISSN - 0976-0083
pISSN - 0974-1496
DOI - 10.31788/rjc.2019.1235033
Subject(s) - oxadiazole , chemistry , combinatorial chemistry , medicinal chemistry , organic chemistry
Synthesis and biological evaluation of novel oxazolidinone derivatives via Schiff’s base formation has been studied. Synthesis involves cyclocondensation of novel Schiff’s base moieties of previously known 1, 3, 4-oxadiazole with chloro acetyl chloride to give a biologically active compound with good yields. All newly synthesized compounds were confirmed by NMR, IR and elemental study. Biological screening for their antibacterial and antifungal activities have been also studied.
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