HIGHLY EFFICIENT STEREOSELECTIVE SYNTHESIS OF βAMINO ACIDS BY ASYMMETRIC METHOD

β-amino acids are the important building blocks for the production of medicines, a precursor for β lactams and building blocks for oligomers. The present study illustrates, novel and efficient asymmetric method for the synthesis of β amino acids has been described. So, the present work deals with the transformation of chiral aspartic acid to β, γ-aziridine carboxylic acid ester, a key precursor followed by regio-and stereoselective ring opening would produce a large number of β-amino acids. This discovery could provide a scope for the large-scale preparation of β-amino acids and their derivatives